Disease, Illness and Condition Library



    Athlete's Foot

    The thought provoking phrase “Athlete’s Foot” is used to describe an
    extremely common skin disease that affects the shoe wearing population
    around the world. It has been estimated that up to 40 percent of American
    will suffer at some time from this infection of the outer layer of the skin.

    Doctors have historically considered athlete’s foot to be a simple fungal
    infection. However, studies performed in the mid 90’s showed that bacteria
    can also play a key role. It is now clear that bacteria, moisture, and fungi
    participate in a complex interaction that leads to development of the severe
    forms of athlete’s foot.

    Athlete’s foot is characterized in its mild form by minor scaling and itching in
    the spaces between the toes. The mildly itchy annoyance can evolve into an
    incapacitating disease characterized by foul smelling, soggy, cracked, and
    ulcerated skin. The spaces between the third, fourth, and fifth toes are most
    commonly involved, although the infection can spread to the soles of the feet
    and to the toenails.

    Common Causes

    Moisture – It has long been estimated that moisture plays an important role in
    producing athlete’s foot. While the condition is almost non existent among
    primitive peoples who do not wear shoes, it is a common problem of all shoe
    wearing populations. It is particularly common among athletes, whose feet are
    continually moist from perspiration and in warm climates, where people tend to
    sweat more. It is believed by enclosing the feet so that sweat cannot evaporate,
    shoes produce the ideal moist environment for athlete’s foot. Furthermore
    because the third, fourth, and fifth toes are so close together, sweat is trapped
    in the spaces between them. Individuals, whose toes are naturally fat and thus
    especially close together, are particularly prone to athlete’s foot.

    Fungi – It has been estimated that 10 to 20 percent of the world’s population
    harbor fungi between their toes at any given time. These are dermatophytes, skin-
    loving fungi that thrive in warm, moist environments, and feed on keratin,
    a protein in the layer of the dead cells on the surface of the skin. For years
    dermatophytes were thought to be solely responsible for causing athletes foot
    because they could be recovered more frequently from the spaces between the
    toes of diseased feet than from normal healthy feet without any evidence of the
    disease. However, the fungi were sometimes present on normal healthy feet
    without evidence of the disease. And in approximately 70 percent of cases of
    severe athlete’s foot, scientists could not find any fungi. This fact was frequently
    played down. Medications were routinely tested only on patients afflicted with
    the mildest forms of athlete’s foot, concealing the fact that the treatment of the
    severe form with antifungal products was frequently ineffective.

    Bacteria – Studies at a number of universities focused on why fungi are not
    always present in athlete’s foot and investigated the factors that caused mild
    athlete’s foot to evolve into the severe form of the disease. It seem that in mild
    cases of athlete’s foot, if the amount of moisture trapped between the toes
    increases, the number of dermatophytes also increases. As the fungi increases
    in numbers, they damage the skin, thus weakening its ability to act as a barrier
    against infection. They also produce antibiotics, including penicillin and
    streptomycin, locally in the skin. This has an important effect on the bacteria
    that are normally present in the skin. It kills many of them off and encourages
    the growth of more dangerous antibiotic resistant bacteria. Like the fungi the
    harmful bacteria thrive in moisture. And as the numbers of these bacteria
    increase in the spaces between the toes, they release substances that further
    damage the skin. Ironically, these substances also kill the local fungi, which is
    why cultures from the patients with severe athlete’s foot routinely show no fungi.

    Treatment

    Once the origin and development of athlete’s foot are understood, it is not
    surprising to find a dermatologist promoting dryness as the most effective
    treatment. Keeping the feet dry not only reduces fungal overgrowth, but also
    limits the bacterial growth seen in severe cases of the disease.

    Removing shoes when possible, changing sock frequently, avoid footwear that
    promotes sweating and instead wearing sandals or other well ventilated and
    loose fitting shoes, dusting the feet and outside the toes with talcum powder
    and using gauze to separate the toes are all highly effective in promoting
    dryness. In most patients these common sense practices clear up
    athlete’s foot.

    In addition, in severe cases dermatologists frequently apply aluminum chloride
    solutions or aqueous dye solutions such as gentian violet to the affected skin.
    These agents produce an additional drying effect, but they also have a potent
    antibacterial effect. Another group of antifungal agents for the treatment of
    athlete’s foot are imidazole compounds. These are actually highly effective
    even for severe athlete’s foot and also have an antibacterial effect.

    Prevention

    It probably comes as no surprise that keeping the feet dry and clean is very
    important in preventing athlete’s foot. After bathing the feet should be
    thoroughly dried, especially between the toes. A light sprinkling of powder
    on the feet and in the shoes to absorb moisture will help keep them that way.
    Shoes should be allowed to air out and dry between uses. Sandals, open toed
    shoes, or thongs, should be worn as much as possible, weather permitting.


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