Disease, Illness and Condition Library


    Anxiety Disorder

    Movies are great at creating a certain amount of anxiety. We have all
    watched one of those old westerns; you know the ones I am talking about,
    where it all comes down to the last minute gun fight scene. The two
    combatants are standing in the street, the music plays, sweat rolls off of
    the bad guys face, and in a flash it is over. But what if the scene played
    on, over and over again? Where the anxiety lingered; this is what people
    with serious anxiety disorders are dealing with, but worse. Their glass always
    seems to be half full. The feeling of what can go wrong will go wrong; also
    known as Murphy’s Law. I don’t know who Murphy was, nor do I want to know,
    but he must have had a serious case of anxiety disorder. I wonder if Murphy
    ever got some much need help? I certainly hope so!

    Anxiety is a far greater problem than originally believed affecting around
    70 million people annually in North America alone. It is also the most common
    of all mental health concerns and affects people of all ages and is thought to
    affect more women than men.

    Anxiety disorder is the little sister of panic disorder. A large number of people
    do not have full panic attacks, but do have generalized anxiety disorder.
    GAD for short, is a chronic and overstated tendency to worry for little or
    no reason.

    Common General Anxiety Disorder Symptoms:

    * Dizziness
    * Sweating
    * Shallow breathing
    * Forgetfulness
    * Headaches
    * Shaking or Trembling
    * Insomnia
    * Chronic fatigue

    Other symptoms include: sweaty palms, severe headaches, neck pain,
    racing heartbeat that will not slow down, hot flashes, rectal bleeding, and
    blackouts. One interesting fact is that symptoms can occur on a regular
    basis or just in specific situations.

    If you are dealing with acute anxiety disorder you may become fearful of
    visiting public venues or being alone. The fear of public places in itself
    increases the level of anxiety present. Until recently many psychologists
    believed that anxiety was a self induced trauma. There was an excellent
    move a few years ago about a fictional writer named “Forrester”.  This movie gave
    a compelling overview of the challenges people face when dealing with anxiety
    and panic disorders.

    The realization that anxiety was a real physical condition didn’t become
    apparent until study after study confirmed that these disorders have genuine
    physical basis. Researchers now believe that anxiety and panic attacks are
    caused by a malfunction in brain chemistry. Put simply the brain is sending
    and receiving false emergency signals. Continued research in the field of
    anxiety has also determined a genetic link between women and anxiety.

    As mentioned about anxiety disorder is a milder form of panic disorder.
    Many suffers feel a vague sense of anxiety much of the time, but the
    intensity of the feeling does not reach the levels of a full blown panic
    attack. People with anxiety challenges will tend to startle easily and feel
    uncomfortable around other people. It is no wonder that headaches and
    chronic fatigue are two of the more common symptoms associated
    with anxiety

    Anxiety disorder may be a condition people are genetically predisposed and
    it seems to run in families. Some cases may even be directly linked to an
    abnormality in heart function called mitral valve prolapse. Anxiety disorder can
    come about in many different ways, but medical experts are in agreement that
    conflict, whether internal or external in nature, promotes a state of anxiety and
    that now brings us to stress.

    Stress a Major Factor

    Athletes want the ball in stressful situations but for those with anxiety
    disorders the ball would be the last thing they would want to see coming.
    The reason is stress is the number one trigger for anxiety. Some numbers
    have stress related doctors office visits as high as 80 percent of total doctor
    visits. Over 60 percent of women say stress is their number one problem.

    Some anxiety is actually normal, and can be helpful in alerting us of
    dangerous situations, but for some stress overload can cause disabling
    symptoms. Anxiety starts to be a problem when a person begins to perceive
    non treating situations as serious threats. Threatening situations trigger
    certain physical responses such as shallow and rapid breathing, as well
    as an elevated heart rate.

    Common Stress Inducers:

    *Divorce and relationship problems
    *Moving
    *Job pressure and deadlines
    *Substance abuse
    *Physical trauma
    *Nutritional deficiencies
    *Job Loss

    Over time chronic stress robs the body of its ability to deal with challenges
    and leads to exhaustion. Certain body organs may fail to function effectively.
    Hormone levels become depleted and serious illnesses such as heart disease
    and cancer often develop. Chronic anxiety can worsen other health problems.
    Anxious people are five times more likely to develop a cold and are more likely
    to have high blood pressure, eating disorders, PMS and headaches just to
    name a few. If you are one of the millions suffering from anxiety you should
    make an attempt to limit the amount of stress in your life.

    Natural and Herbal Therapeutic Considerations for Anxiety

    The natural approach to treating anxiety is closely interrelated to
    that of stress management. After all, as discussed above, anxiety
    is usually a symptom of severe stress.

    Reducing Lactate Levels

    Increased lactic acid levels may be an core factor in panic attacks and
    anxiety. The goal is to prevent the conversion of pyruvic acid to lactic
    acid and to improve the conversion of lactic acid back to pyruvic acid.
    Nutrition appears to play a key role in achieving this goal. According
    to Melvyn Werbach, M.D., author of Nutritional Influences on Mental
    Illness, there are at least six nutritional factors that may be to blame
    for elevated lactate levels or lactic acid to pyruvic acid ratios:

    1.        Alcohol
    2.        Caffeine
    3.        Sugar
    4.        Deficiency o the B vitamins niacin, pyridoxine, and thiamin
    5.        Deficiency of calcium or magnesium
    6.        Food allergens

    By avoiding alcohol, caffeine, sugar, and food allergens, people with anxiety
    can go a long way toward relieving their symptoms. Simply eliminating coffee
    can result in total relief from symptoms. This recommendation may seem too
    simple to be valid, but considerable clinical evidence indicates that in many
    cases it is all that is required. For example, on study dealt with four men and
    two women who had generalized anxiety or panic disorder. Their caffeine
    consumption ranged from 1.5 to 3.5 cups of coffee per day. Avoiding caffeine
    for one week brought about significant relief of symptoms. The degree of
    improvement was so evident that all patients volunteered to continue abstaining
    from caffeine. Up to that time these patients had been only minimally helped by
    drug therapy. Follow up exams six to eighteen months afterward indicated that
    five out of the six patients were completely without symptoms; the sixth patient
    became asymptomatic with very low dose of Valium.

    Flaxseed Oil and Agoraphobia

    It has been suggested that patients who get panic attacks may suffer from
    a deficiency of alpha linolenic acid, the essential omega 3 fatty acid found
    in high concentrations in flaxseed oil. In one study, three out of four patients
    with a history of agoraphobia for ten or more years improved within two to
    three months after taking flaxseed oil at a dosage of 2 to 6 tablespoons daily,
    in divided doses depending upon response. All patients had signs of essential
    fatty acid deficiency, such as dry skin, dandruff, brittle fingernails that grow slowly,
    and nerve disorders.

    Kava (Piper methysticum)

    The area of Oceania – the island communities of the Pacific including
    Micronesia, Melanesia, and Polynesia – is one of the few geographic
    areas in the world that did not have alcoholic beverages before European contact
    in the eighteenth century. However, these islanders did possess a mysterious
    drink that was used in ceremonies and celebrations because
    of its calming effect and ability to encourage sociability. The drink, called
    kava, is still used today in this region, where the people are often referred
    to as the happiest and friendliest in the world. Preparations of kava root are
    now gaining popularity in Europe and the United States as mild sedatives
    and anxiolytics.

    Several European countries have approved kava preparations for the
    treatment of nervous anxiety, insomnia, and restlessness on the basis of
    meticulous pharmacological data and favorable clinical studies.

    Earlier clinical trials used D, L- kavain, a purified kavalactone (the key group
    of compounds in kava), at a dose of 400 mg per day. For example, in one
    double blind placebo controlled study of eighty four patients with anxiety
    symptoms, kavain was shown to improve vigilance, memory, and reaction
    time. In another double blind study, kavain was compared to the drug
    oxazepam (a drug similar to diazepam or Valium) in thirty eight patients.
    Both substances caused progressive improvements in two different anxiety scores
    over a four week period. However, while oxazepam and similar drugs
    are linked to side effects and with being addictive, kavain appeared to be
    free of these complications.

    More recent studies have featured well defined kava extracts. As mentioned
    earlier, evidence suggests that the whole complex of kavalactones and other
    compounds naturally found in kava produce greater pharmacological activity
    than pure kavalactone preparations. In addition, studies have shown that
    kavalactones are more rapidly absorbed when given orally as an extract of
    the root rather than as the isolated kavalactones. The bioavailability of
    kavalactones, as measured by peak plasma concentration, is up to three
    to five times higher form the extract than when given as isolated substances.
    Further evidence that kava root extracts are superior to isolated kavalactones
    is offered by an animal study showing that, while isolated kavalactones are
    taken up into the brain tissue at a good level, when a crude kava preparation
    was given, the concentration of kavalactones was two to twenty times higher.
    Based on this data it appears that crude extracts standardized for kavalactone
    content may offer the greatest therapeutic benefit.

    Several clinical trials have featured a special kava extract standardized to
    contain seventy percent kavalactones. However, this high percentage of
    kavalactones may be sacrificing some of the other constituents that may
    contribute to the pharmacology of kava. Therefore, preparation around
    thirty percent may demonstrate the most effectiveness. More important
    than the actual percentage of kavalactones is the total dosage of the
    kavalactones and the assurance that the full range of kavalactones is
    present.

    In perhaps the most significant study, a seventy percent kavalactone extract
    was shown to exhibit considerable therapeutic benefit in patients suffering from
    anxiety. The study was double blind; twenty nine patients were assigned to
    receive 100 mg of the kava extract three times daily, while another twenty nine
    patients received a placebo. Therapeutic effectiveness was evaluated using
    several standard psychological assessments, including the Hamilton Anxiety
    Scale. The results of this four week study indicated that individuals who took
    the kava extract had a statistically significant reduction in symptoms of anxiety,
    including feelings of nervousness and somatic complaints such as heart
    palpitations, chest pains, headache, dizziness, and feeling of gastric irritation.
    Not side effects were reported with the kava extract.

    In another double blind study, two groups of twenty women with menopause
    related symptoms were treated for a period of eight weeks with the seventy
    percent kavalactone extract (100 mg three times daily) or a placebo. The
    target variable was once again the Hamilton Anxiety Scale. The group that
    received the kava extract demonstrated significant improvement at the end
    of the very first week of treatment. Scores continued to improve over the
    course of the eight weeks study. In addition to reduction in symptoms
    of stress and anxiety, a number of other symptoms were relieved. Most
    notably there was on overall improvement in subjective well being, mood,
    and general symptoms of menopause, including hot flashes. Again, no side
    effects were noted.

    Two additional studies have shown that unlike benzodiazepines, alcohol, and
    other drugs, kava extract is not associated with depressed mental function or
    impairment when driving or the operation of heavy equipment. In one of these
    studies, twelve healthy volunteers were tested in a double blind crossover
    manner. The first group received oxazepam (placebo on days one through
    three, 15 mg on the day before testing, 75 mg on the morning of the
    experiment); the second group received an extract of kava standardized at
    seventy  percent kavalactones (200 mg three times daily for five days), and
    the third group received a placebo. The participants were tested on behavior
    and event related potentials (ERPs) in electroencephalograph (EEG) readings
    in a recognition memory task. Their task was to identify, within a list of visually
    presented words, those words that were shown for the first time and those
    that were being repeated. Consistent with other benzodiazepines, oxazepam
    inhibited the recognition of both new and old words as noted by ERP.
    In contrast, kava showed a slightly increased recognition rate and a larger
    ERP difference between old and new words. The results of this study once
    again reveal the uncharacteristic effects of kava; in this case, it relieves
    anxiety, but unlike standard anxiolytics, kava actually improves mental
    function and at the recommended levels does not encourage sedation.

    The dosage of kava preparations is based on their level of kavalactones.
    As a result of clinical studies using pure kavalactones or kava extracts
    standardized for kavalactones, the recommendation for anxiety relieving
    effects is 45 to 70 mg of kavalactones three times per day. For sedative
    effects, the same daily quantity (135 to 210 mg) can be taken as a single
    dose one hour before retiring.

    To put the therapeutic dosage in context it is important to point out that a
    standard bowl of traditionally prepared kava drink contains approximately
    250 mg of kavalactones, and several bowls may be consumed at one sitting.

    Side Effects of Kava

    While no side effects have been reported using standardized kava extracts at
    recommended levels in the clinical studies, several case reports have been
    presented indicating that kava may interfere with dopamine production or
    binding to receptor sites and worsen Parkinson’s disease, exert an additive
    effect when combined with benzodiazepines, and produce impaired driving
    ability when consumed in very large doses; sixteen cups of kava beverage as
    described below. Until these issues are cleared up, kava extract should not be
    used in treating Parkinson’s patients and should be used with extreme caution
    and close monitoring in patients taking benzodiazepines. Additionally, patients
    should be instructed not to overdose on kava. In Utah, a man was charged
    with driving under the influence after he was stopped for swerving in and
    out of traffic lanes; he admitted to having consumed sixteen cups of kava.
    A cup of kava may contain an entire daily dosage of kavalactones as used
    in clinical studies (210 mg).

    High quantities of kava beverage consumed daily over a prolonged period
    (a few months to a year or more) are associated with kava dermopathy, a
    condition of the skin characterized by a peculiar generalized scaly eruption
    know as kani. The skin becomes dry and covered with scales, especially
    the palms of the hands, soles of the feet, forearms, back, and shins. It was
    thought at one time that kava dermopathy might be due to interference with
    niacin. However, in a double blind placebo controlled study, no therapeutic
    effect from niacinamide supplementation (100 mg daily) could be
    demonstrated. It appears that the only successful treatment for kava
    dermopathy is reduction or cessation of kava consumption. Again, no
    reported cases of kava dermopathy have been noted in individual
    taking standardized kava extracts at recommended levels.

    Additional adverse effects of extremely high doses of kava (greater than 310
    grams per week) for extended periods include: biochemical abnormalities (low
    levels of serum albumin, protein, urea, and bilirubin), presence of blood in the
    urine, increased red blood cell volume, decreased platelet and lymphocyte
    counts, and shortness of breath. The correlation of these adverse effects with
    kava is questionable because the subjects also reported heavy alcohol and
    cigarette usage. Nevertheless, high doses of kava are unnecessary and
    should not be encouraged.

    St. John’s Wort (Hypericum perforatum) has been traditionally used for centuries
    to support balanced mood and safely maintain mental wellness and equilibrium.
    In recent times, clinical studies have confirmed ancient wisdom and Hypericum is
    one of the most widely studied herbs on the market today. Active ingredients
    include glycosides, flavonoids, volatile oils, tannins and resins. St. John’s Wort
    has also been shown to support stable mood during the menstrual and
    premenstrual periods. (Stevinson C, Ernst E. A pilot study of Hypericum
    perforatum for the treatment of premenstrual syndrome. British Journal of
    Obstetrics and Gynaecology. 2000;107:870-876).

    Passionflower: The herb passionflower (Passiflora incarnata) was used as a folk
    remedy for anxiety and insomnia.

    Two studies involving a total of 198 people examined the effectiveness of
    passionflower for anxiety. One study found passionflower to be comparable to
    benzodiazepine drugs. There was also improvement in job performance with
    passionflower and less drowsiness with passionflower compared with the drug
    mexazolam, however, neither was statistically significant.

    Side effects of passionflower may include nausea, vomiting, drowsiness, and
    rapid heartbeat. The safety of passionflower in pregnant or nursing women,
    children, or people with kidney or liver disease has not been established. There
    have been five case reports in Norway of people becoming temporarily impaired
    mentally after using a combination product containing passionflower. It's not
    known whether the other ingredients in the supplement played a role.

    Passionflower should not be taken with sedatives unless under medical
    supervision. Passionflower may enhance the effect of pentobarbital, a
    medication used for sleep and seizure disorders.

    General Suggestions for Dealing with Anxiety

    Exercise – When the going gets tough the tough get going. We have all heard
    this saying but when it comes to anxiety it just may hold true. Anxiety and panic
    increase your stress level, and exercise tends to reduce it. A good idea is if you
    are feeling anxious is to take a fast walk, or bicycle ride. Who knows, you may
    have an entirely different perspective when you finish.

    Audio for Therapy – Listening to music, gentle sounds, or self help tapes.
    This just might be what is needed you squash that nervous feeling.

    Breathe Deep – Athletes have used breathing as a tool for years to relieve
    anxiety and you should too. Breathe in, hold for a few seconds and then
    slowly release; repeat five times. Another idea is to breathe in slowly and
    breathe out slowly, visualizing the tide flowing in and the tide flowing out.

    Audio Diary – Talk to yourself about your fears and concerns, and then play
    the tape back to see if your fears are exaggerated. Most experts suggest you
    listen to your tape multiple times to get used to it, taking some of the emotion
    out. Once the emotion is gone, you are much better equipped to analyze
    it sensibly.

    Let Go – Stop worrying about things you can’t control. If the mailman is
    an hour late, society as we know it will not end. In fact the mail will
    probably come tomorrow, and hopefully on time.


    Natural Supplements for Anxiety and Stress

    PureCalm- Reduce Stress & Anxiety While Balancing Moods
    PureCalm can been used to safely maintain harmony, health and systemic
    balance in the brain and nervous system, without harmful side effects and
    without sedatives. This remedy contains a selection of herbs known for their
    supportive function to reduce stress, balance moods, and maintain healthy
    brain function.
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    MindSoothe - Treat Anxiety and Panic Disorder Naturally
    MindSoothe is a 100% safe, non-addictive, natural herbal remedy that
    has been especially formulated by a Clinical Psychologist for adults and
    teens, and comes in a compact capsule form, making it easy to take.
    MindSoothe can be used to safely maintain health, uplifted mood and
    systemic balance in the brain and nervous system, without harmful side
    effects and without harsh sedatives.
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    Mood Tonic - Improve Mood and Reduce Anxiety
    Lessen general feelings of the blues and promote a healthy balanced mood.
    Triple Complex Mood Tonic is a 100% natural combination of three, cellular-
    supporting tissue salts, especially selected for their effect on brain structures,
    brain chemistry and nervous system health.
    Continue
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